In the last decades, millions of people have been exposed to various forms of silicone. Silicone’s chemical structure and the many changes since its launch have also raised many problems and questions about its local, as well as systemic, interactions. CC formation displays the result of a fibrotic foreign body reaction after implantation of silicone breast prostheses in the human body.,,,– This physiological reaction of the body to the silicone implant, forming a fibrous capsule, reflects two sides of a coin: on the one hand, it maintains the correct positioning of the implant, but on the other hand, it is associated with pain, hardening, tightness, deformity, and distortion of the breast. Furthermore, capsular fibrosis is the number one reason for revision operations, especially in implant exchange procedures, as capsular fibrosis does not occur that frequently in primary augmentations compared with in reconstruction/revision procedures., The formation of a fibrous capsule is part of a process of protection of the organism from foreign material, which can be formed within 1–2 weeks postoperatively. The myofibroblast displays one of the predominant cell types of the capsule, however, and is accompanied by macrophages, polymorphonuclear leukocytes, lymphocytes, plasma cells, and mast cells.– The capsule thickness consists of approximately 27% myofibroblasts, with increasing tensile strength according to the degree of contracture. Interestingly, this is not correlated with the number of fibroblasts. The cellular source of the myofibroblast seems to be the bone marrow, as shown by Isom et al, who found 25% of bone marrow-derived stem cells in textured silicone shells in mice. Prantl et al further demonstrated that capsular thickness was associated with the number of silicone particles and silicone-loaded macrophages in the peri-implant capsule and with an increased local inflammatory reaction., These histological findings, which were classified by the Wilflingseder score, correlated well with the clinical Baker classification (, ). In addition, it could be demonstrated that serum hyaluronan levels, as well as circulating immune complexes, procollagen III, antipolymer antibodies, and soluble intercellular adhesion molecule 1 (sICAM-1), were significantly elevated in patients with CC, also correlating in part with the clinical Baker stage of contracture. After multiple experimental and clinical trials, there seems to be a strong consensus that the use of textured outer shell surfaces, in comparison with smooth surfaces, is able to decrease the incidence of CC by disrupting contractile forces around the implant,,– emphasizing the need for better physical properties than cellular or pharmacological strategies of contracture formation.
These will give you the perfect pec curves in which means you can pass like a massive woman.
Prosthesis, or breast forms, is another excellent alternative to surgery.
Breast reconstruction after a mastectomy due to cancer or other disease is an option that is now available to almost all women who desire it. A woman might be reminded of her cancer when she sees the mastectomy scar on her chest instead of a breast in the mirror each morning. Another woman might be bothered by the prosthesis that she has to wear in her bra. Although no reconstructed breast is as nice as a natural breast, surgical techniques and devices developed over the past several years have made it possible for Dr. Eich, a breast reconstructive surgeon in Birmingham, to create a breast that can help a woman regain her self-image and try to put the cancer in the past.
Dr. Eich performs breast reconstruction under general anesthesia in St Vincent’s East Hospital in Birmingham, which is convenient for most of central Alabama including Anniston, Gadsden, and Tuscaloosa.
If a tissue expander is to be used for breast reconstruction, it will be placed in a pocket under the chest muscle, and the fill port will be located close to the collarbone.
In a TRAM flap reconstruction, an oval section of skin, fat and muscle is taken from the lower half of the abdomen and moved upwards through a tunnel under the skin up to the breast area. The tissue is then formed into a breast mound and sutured in place. The defect in the abdomen where the tissue was removed is then closed and sutured.
The tissue expander operation takes about an hour, and patients can usually go home the day of surgery unless the mastectomy is done at the same time. In that case, patients will usually spend 2 nights in the hospital. The TRAM flap takes about 4-5 hours, and patients usually spend 3-4 nights in the hospital.