Chemical Reagents: 2.0 g of salicylic acid (C H O )
4.0 mL of acetic anhydride (C H O )
7 drops of 85% phosphoric acid (H PO )
100 ml of ice-cold distilled water (H O)
3 ice cubes (H O)
18 drops of 1% ferric chloride solution (FeCl ) Chemical Reagents: Potassium Hydrogen Phthalate (KHP) (KHC H O )
Sodium Hydroxide (NaOH)
distilled water (H O) Data Table: Trial (KHP titration) 1 2 3 Mass of KHP (g) Initial Burette Reading (mL) Final Burette Reading (mL) Volume Used (mL) .436 .473 .527 0.00 0.00 0.00 22.50 24.10 26.80 22.50 24.10 26.80 Balanced Equation: Procedure Step 2
A solution of approximately 0.1 Molar NaOH was prepared by weighing out 4 grams of NaOH into a 1 liter plastic bottle.
What is the chemical equation for the synthesis of aspirin The chemical equation for the synthesis of aspirin is C7H6O3 + C4H6O3 -> C9H8O4 +C2H4O2, which is a reaction of salicylic acid with acetic anhydride in the presence Synthesis of Aspirin Notes Synthesis of Aspirin Notes Here is the balanced equation for the What is the difference between the solid we produce in lab and aspirin Experiment 5 – Synthesis of Aspirin locker until the next lab period. Now set the y-intercept to 0 and check the display equation box. To add Experiment 5 – Synthesis of Aspirin Preparation of Acetylsalicylic Acid (Aspirin) PREPARATION OF ACETYLSALICYLIC ACID (ASPIRIN) Pure Acetyl Salicylic Acid (Aspirin) SYNTHESIS Chemistry It can be dried on the laboratory ventilators. Chemistry 51 Experiment 11 Synthesis and Analysis of Aspirin Experiment 11 Synthesis and Analysis of Aspirin INTRODUCTION Write the chemical equation for the reaction of aspirin and water at high temperatures. 4. How to Make Aspirin – Acetylsalicylic Acid – ThoughtCo In this laboratory exercise, you can prepare aspirin used to synthesize the aspirin: Aspirin Synthesis "How to Make Aspirin – Acetylsalicylic Acid Bellevue College | CHEM& 161 Titration of Synthesized Aspirin Titration of Synthesized Aspirin A continuation of the aspirin synthesis lab according to the balanced equation. 81 experiment – Chem21Labs Synthesis of Aspirin. 82 When you perform a chemical synthesis in lab, stoichiometry of the equation, how many moles of
Ferric Chloride Test for Purity Chemical Reagents: .1M HCl, standardized
.1M NaOH, standardized
Phenolphthalein solution Step 1 Approximately .5g of the synthesized aspirin was weighed and placed into a 250mL Erlenmeyer flask.
He also synthesized Aspirin because his father, who had severe arthritis, could not tolerate the salicylic acid he was taking for pain relief.
The Kolbe Synthesis for the production of salicylic acid was created by the German chemist Hermann Kolbe.
Aspirin is prepared in the laboratory by simply adding ethanoic anhydride to salicylic acid in the presence of concentrated sulfuric acid and leaving the mixture to react or some 15 minutes. The excess ethanoic anhydride is destroyed by the addition of water. The aspirin can be collected by cooling in ice, filtering and may be purified by recrystallisation from an ethanol/water mix.
From the above equation, it can be seen that the degradation of aspirin in asolution buffered at pH = 7.5 will follow first order kinetics; that is,the reaction will appear to be a first order reaction, dependent only onthe concentration of one reactant; i.e. aspirin.
In 1899, the Bayer Company in Germany patented an ester of salicylic acid, acetylsalicylic acid, and marketed the product as aspirin. Their studies showed that this ester was somewhat less of an irritant (pKa = 3.5). It is known today that acetylsalicylic acid is hydrolyzed in the small intestine to salicyclic acid, and is then absorbed into the bloodstream.
Hydrolysis of the drug entity can be a major factor in the instabilityof solutions. Aspirin, for example, undergoes hydrolysis with the resultantdegradation products being salicylic acid and acetic acid. The rate ofthis reaction is said to be second order, since it is dependent not onlyupon the aspirin concentration, but upon solution pH (i.e. the hydroniumion concentration at solution pH values less than approximately 2.5 orthe concentration of hydroxyl ion at solution pH values greater than approximately7.0). At pH = 7.5, the rate expression for the hydrolysis of aspirin maybe written:
A. What is the limiting reagent? [The limiting reagent is O2.]
B. What mass of water could be formed? [304 g H2O]
THEORETICAL YIELD is the amount of product that can be obtained from a given
amount of reactants, according to the chemical equation.
Biodiesel is produced by chemically reacting a fat or oil with an alcohol, in the presence of a catalyst. The product of the reaction is a mixture of methyl esters, which are known as biodiesel, and glycerol, which is a high value co-product. The process is known as transesterification, as shown in the equation in the animations below, where R1, R2, and R3 are long hydrocarbon chains:
Further Analysis THE END Presented by MY LIFE: YOU LIGHT IT UP Conclusion The overall objectives of this experiment were to synthesize aspirin, to perform a crude purity test on said aspirin, to standardize and prepare solutions of both NaOH and HCL, and to qualitatively determine the purity of the aspirin by finding the percentage of acetylsalicylic acid in the aspirin.