mode of action inhibit synthesis of acid-fast cell walls, inhibits elongation of the protein result blocks translation of mRNA into protein, binds to 50S ribosomal subunit examples oxazolidinones, binds to 30S ribosomal subunit examples aminoglycosides, bacitracin action binds to bactoprenol, interferes with the binding of the 50S subunit to the initiation complex result blocks translation of mRNA into protein, aminoglycosides action prevents the transfer of the peptidyl tRNA from the A-site to the P-site, fluoroquinolones action inhibits bacterial topoisomerase enzymes, antibiotic/chemical agent binds to prokaryotic ribosomal subunits ????
Presentation Summary : Inhibitors of Protein Synthesis Bacterial cells are 50% protein by dry weight Inhibition of protein synthesis leads to cessation of growth or cell death
The toxin inhibited protein synthesis after all 3 schedules of treatment and inhibition was present in cells obtained from bone marrow, spleen, and thymus.
Photosynthesis as well as the activity of glutamate dehydrogenase and alanine aminotransferase were similarly inhibited, but there was no pronounced effect on dark respiration.
They reported that NIV produced a dose-dependent inhibition of incorporation of several amino acids into protein in rabbit reticulocytes (Ueno et al., 1968) and Ehrlich ascite tumour cells (Ueno & Fukushima, 1968).
Presentation Summary : Antibiotics Antibiotics are ... by Streptomyces Inhibits protein synthesis on the 70S ribosomes ... Sulfanilamide Competitive inhibitor Inhibits folic acid synthesis. ...
Presentation Summary : Topical Antibiotics Like other aminoglycosides, neomycin works by binding to the bacterial 30S ribosomal subunit, thus inhibiting protein synthesis.
Presentation Summary : Protein Synthesis Inhibitors. Many antibiotics bind specifically to the bacterial ribosome. binding can be to 30S (small) or 50S (large) ribosomal subunit.
Presentation Summary : Antimicrobial Agents ... of cell wall synthesis Inhibition of protein synthesis ... ribosomes make antibiotics that target protein synthesis fairly ...
Presentation Summary : antibiotics active against one or very few types, e.g., ... Inhibition of protein synthesis. 50S . 30S. Chloramphenicol, erythromycin, clindamycin, linezolid,
Presentation Summary : Antibiotics I. Consequences of ... cell wall synthesis inhibitors protein synthesis inhibitors nucleic acid synthesis inhibitors cytoplasmic membrane function ...
Cephalosporins PPT Presentations : Cephalosporins B-Lactam antibiotics ( similar to penicillins) Broad spectrum Act by inhibition of cell wall synthesis Bactericidal Inactive against : enterococci , cephalosporin .ppt, penicillins and cephalosporins ppt, synthesis of b-lactam antibiotics ppt, classification of cephalosporins ppt, cephalosporins power point, cephalosporins ppt, mechanism of action of cephalosporins ppt, cephalosporin drug .ppt, quinolone and .ppt, cephalosporins, Cephalosporins is great presentation for you. If It's helpful for your subject then you will click the link
"" get it free.
Thanks for choosing us.
Presentation Summary : Antibiotics have been found to have different modes of action to inhibit bacteria:destruction of cell wall destruction of cell membrane inhibition of protein ...
TRICHOTHECENES II.1 Properties and analytical methods II.1.1 Physical and chemical properties II.1.1.1 Physical properties II.1.1.2 Chemical properties II.1.2 Analytical methods for trichothecenes II.1.2.1 Chemical methods II.1.2.2 Immunological methods II.1.2.3 Biological methods II.2 Sources and occurrence II.2.1 Taxonomic considerations II.2.2 Ecology of trichothecene-producing fungi II.2.3 Natural occurrence II.2.3.1 Agricultural products II.2.3.2 Trichothecenes in human foodstuffs II.3 Metabolism II.3.1 Absorption and tissue distribution II.3.1.1 Animal studies II.3.2 Metabolic transformation II.3.3 Excretion II.3.3.1 Animal studies II.3.3.2 Excretion in eggs and milk II.4 Effects on animals II.4.1 Field observations II.4.2 Effects on experimental animals II.4.2.1 General toxic effects II.4.2.2 Haematological and haemostatic changes II.4.2.3 Disturbances of the central nervous system II.4.2.4 Dermal toxicity II.4.2.5 Impairment of immune response II.4.2.6 Carcinogenicity II.4.2.7 Mutagenicity II.4.2.8 Teratogenicity and reproductive effects II.4.3 Biochemical effects and mode of action II.4.3.1 Cytotoxicity II.4.3.2 Inhibition of protein synthesis II.4.3.3 Inhibition of nucleic acid synthesis II.4.3.4 Alterations of cellular membranes II.4.3.5 Other biochemical effects II.4.4 Structure-activity relationships II.4.5 Prevention and therapy of trichothecene toxicosis II.5 Effects on man II.5.1 Contemporary episodes of human disease II.5.2 Historical Fusarium-related diseases II.5.3 Skin irritation II.5.4 Studies of haemostasis II.5.5 Airborne trichothecene-related diseases II.5.6 Toxicological information on man, obtained from therapeutic uses II.6 Evaluation of the human health risksIII.
Presentation Summary : ... no such antibiotic exists Mechanisms of action Cell wall synthesis inhibitors Cell membrane inhibitors Protein synthesis inhibitors ... Antimicrobial Therapy ...