Compound: Color after ferric chloride was added
We diluted 17 mL of the 3 Molar HCl to 500 mL in the provided reagent bottle
We filled each burette with their solutions and recorded the initial burette readings
We drained 20 mL of acid from the acid burette in to the 100 mL beaker and added 3 drops of bromthymol blue indicator.
We titrated with base until the solution was a faint green and recorded the final burette reading
Quantitative Analysis of Aspirin
To determine the purity of synthesized aspirin and the percentage of acetylsalicylic acid present in your synthesized product by using back titration.
syntheized aspirin from module #1
250 mL Erlenmeyer flask
0.1 M Hydrochloric acid (HCl)
0.1 M Sodium Hydroxide (NaOH)
Phenolphthlein solution (C20H14O4)
We weighed 0.500g of the synthesized aspirin and placed it into the 250 mL Erlenmeyer flask
We cooled 25 mL of ethyl alcohol to 15 degrees Celcius and added it to the flask containing the aspirin and swirled to dissolve.
We added two drops of phenolphthalein and rapidly titrated the sample with the standard NaOH solution until it reached a faint pink color.
We rapidly titrated with NaOH until the light pink color was achieved.
We added 6 drops of 1% ferric chloride solution to all three test tubes and observed the color of each tube
1 Liter plastic bottle
100 mL Beaker
Calculate the molarity of the acid solution in each trial and determine the average concentration of the HCl.
3 M Hydrochloric Acid (HCl)
Sodium Hydroxide (NaOH)
Bromthymol blue (?)
The purpose of this experiment is to synthesize aspirin and to perform a crude purity test on your product.
When was aspirin first synthesized, by whom, and for what purpose?
A German chemist by the name of Felix Hoffman was the first to synthesize aspirin in 1897.
Oxi-2 MT - Specific MT formulation for the Fast Oxidizer Dominant, designed to decrease the Oxidation Rate*. Creation of this proprietary and unique formulation carefully considered not only specific nutrients, but equally important, matched the specific nutrient carriers to the intended metabolic effect on both the target system as well as body pH. The combination of these elements makes this formulation unique and incredibly effective for its purpose*. Each capsule contains: Vitamins: 2500 I.U. A, 40 mg. B3, 20 mg. B5, 400 mcg. B12, 157 mg. C, 60 mg. Choline, 42 I.U., E, 30 mg. Inositol, 20 mg. Intrinsic Factor. Minerals: 118 mg. Calcium, 50 mcg. Iodine, 62 mg. Phosphorus, 7 mg. Zinc. Amino Acids: 35 mg. L-Carnitine, 22 mg. L-Isoleucine, 46 mg. L-Leucine, 34 mg. L-Lysine, 26 mg. L-Phenylalanine, 7 mg. L-Tryptophane, 22 mg. L-Threonine, 19 mg. L-Tyrosine. Misc.: 15 mg. Betaine, 15 mg. Quercetin, 35 mg. RNA, 15 mg. Rutin. 90 capsules
The synthesis of aspirin is classified as an esterification reaction. Salicylic acid is treated with acetic anhydride, an acid derivative, causing a chemical reaction that turns salicylic acid's hydroxyl group into an ester group (R-OH → R-OCOCH3). This process yields aspirin and acetic acid, which is considered a byproduct of this reaction. Small amounts of sulfuric acid (and occasionally phosphoric acid) are almost always used as a catalyst. This method is commonly employed in undergraduate teaching labs.