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Regulation of de novo pyrimidine biosynthesis ..

The model is able to faithfully represent the dynamic changes in the intracellular nucleotide pools that occur during metabolic transitions of the de novo pyrimidine biosynthetic pathway and represents a step forward in understanding the role of allosteric regulation in metabolic control.

The biosynthetic pathway of de novo pyrimidine nucleotide metabolism is an essential capability of all free-living cells, and it occupies a pivotal position relative to metabolic processes that are involved in the macromolecular synthesis of DNA, RNA and proteins, as well as energy production and cell division.

06/12/2012 · Regulation of de novo purine biosynthesis 8 ..

Nucleotide Metabolism: Nucleic Acid Synthesis

Nucleotide Biosynthesis (De-novo & Salvage Synthesis of Purine & Pyrimidine Nucleotides …

The model is able to faithfully represent the dynamic changes in the intracellular nucleotide pools that occur during metabolic transitions of the de novo pyrimidine biosynthetic pathway and represents a step forward in understanding the role of allosteric regulation in metabolic control.">

Activation of Ribose-5-Phosphate

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Purine and Pyrimidine Metabolism - Spencer S


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