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They would then propose a hypothesis about how these two variables are related, such as "test anxiety decreases as a result of effective study habits."

In the scientific method, falsifiability is an important part of any valid hypothesis. This does not mean that the hypothesis is false; instead, it suggests that if the hypothesis were false, researchers could demonstrate this falsehood.

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Hypothesis Definition, Checklist, and Examples

In psychology, the hypothesis might focus on how a certain aspect of the environment might influence a particular behavior.

The hypothesis is what the researchers' predict about the relationship between two or more variables, but it involves more than a guess. Most of the time, the hypothesis begins with a question which is then explored through background research. It is only at this point that researchers begin to develop a testable hypothesis.

In a study exploring the effects of a particular drug, the hypothesis might be that researchers expect the drug to have some type of effect on the symptoms of a specific illness.

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Unless you are creating a study that is exploratory in nature, your hypothesis should always explain what you expect to happen during the course of your experiment or research.

For example, last summer Genentech  of a phase II trial testing the efficacy of crenezumab to treat Alzheimer’s disease.

A proposed model for the dephosphorylation, activation, and translocation of actin depolymerizing factor (ADF) to the apical microvilli during ischemia. Under physiological conditions, the distribution of ADF and phosphorylated ADF (pADF) in proximal tubule cells is diffused throughout the cytoplasm with little or no localization to the apical microvillar region. With ischemia, pADF is dephosphorylated and, therefore, activated. In addition, the diffused cytoplasmic localization of ADF changes with ADF now concentrating at the apical membrane region of the cell. It is hypothesized that ADF relocalizes to the apical microvillar region and binds the microfilament core, resulting in markedly enhanced filament severing and depolymerization. Breakdown of the microfilament core is accompanied by dramatic changes in the overlying microvillar membrane. The microvillar membrane is internalized or extruded as membrane vesicle or blebs. These vesicles contain both ADF and monomeric actin. Figure and legend adapted, ith permission, from reference .

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In the previous example we saw both stratum-specific estimates of the odds ratio went to one side of the crude odds ratio. With effect modification, we expect the crude odds ratio to be between the estimates of the odds ratio for the stratum-specific estimates.

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This is one way to demonstrate the presence of confounding. You may have a priori knowledge of confounded effects, or you may examine the data and determine whether confounding exists. Either way, when confounding is present, as in this example, the adjusted odds ratio should be reported. In this example, we report the odds-ratio for the association of diabetes with CHD = 2.84, adjusted for hypertension.

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Nondifferential misclassification: the probability of misclassification does not vary for the different study groups; is not conditional upon exposure or disease status, but appears random. Using the above example, if half the subjects (cases and controls) were randomly selected to be interviewed by the phone and the other half were interviewed in person, the misclassification would be nondifferential.

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Even in situations where the hypothesis is unsupported by the research, this does not mean that the research is without value. Not only does such research help us better understand how different aspects of the natural world relate to one another, it also helps us develop new hypotheses that can then be tested in future research.

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Are we more likely to misclassify cases than controls? For example, if you interview cases in-person for a long period of time, extracting exact information while the controls are interviewed over the phone for a shorter period of time using standard questions, this can lead to a differential misclassification of exposure status between controls amd cases.

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The hypothesis is a critical part of any scientific exploration. It represents what researchers expect to find in a study or experiment. In some cases, the original hypothesis will be supported and the researchers will find evidence supporting their expectations about the nature of the relationship between different variables. In other situations, the results of the study might fail to support the original hypothesis.

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Descriptive research such as , and surveys are often used when it would be impossible or difficult to . These methods are best used to describe different aspects of a behavior or psychological phenomenon. Once a researcher has collected data using descriptive methods, a can then be used to look at how the variables are related. This type of research method might be used to investigate a hypothesis that is difficult to text experimentally.

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Once a researcher has formed a testable hypothesis, the next step is to select a research design and start collecting data. The research method a researcher chooses depends largely on exactly what they are studying.

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