Rhodiola rosea extract activated the synthesis or resynthesis of ATP in
mitochondria and stimulated reparative energy processes after intense exercise.
[A6] The effects of oral treatment with extracts from Rhodiola rosea
(dosage 50 mg/kg) and Rhodiola crenulata (dosage 50 mg/kg) roots on the duration of exhaustive swimming and ATP content in mitochondria of
skeletal muscles was studied in rats.
Adenosine Triphosphate (ATP) stores in the muscle last for approximately 2 seconds and the resynthesis of ATP from Creatine Phosphate (CP) will continue until CP stores in the muscles are depleted, approximately 4 to 6 seconds. This gives us around 5 to 8 seconds of ATP production.
The result of muscle contraction produces ADP which when coupled with CP regenerates ATP. Actively contracting muscles obtain ATP from glucose stored in the blood stream and the breakdown of glycogen stored in the muscles. Exercise for longer periods requires the complete oxidation of carbohydrates or free fatty acids in the mitochondria. Thestore will last approximately 90 minutes and the free fatty store will last several days.
The aerobic energy system utilises proteins, fats and carbohydrate (glycogen) for resynthesising ATP. This energy system can be developed with various intensity (Tempo) runs.
The human body is also capable of resynthesising ATP to allow it to continue producing energy. To do this it must use energy to reverse the equation shown above. This is known as an endothermic reaction as it requires energy. The breakdown of ATP is called exothermic as it produces energy. The process of breaking down and resynthesising ATP is efficient at producing energy as less energy is required to resynthesis the ATP than is made to break it down. Here is the Resynthesis equation: