Tius Chapter 20: Transannular cyclization in natural product totalsynthesis Jiong Yang and Haoran Xue Chapter 21: Cascade reactions in stereoselective synthesis Bor-Cherng Hong and Nitin S.
Dange Chapter 22: Sulfur dioxide: a powerful tool for thestereoselective construction of C-C bonds Pierre Vogel, Dean Markovic and Maris Turks Chapter 23: Transition metal C-H activation: application tostereoselective synthesis of natural products and drugs Mickael Jean and Pierre van de Weghe Chapter 24: Metathesis reactions in drug and natural productsynthesis Akio Saito, Yuji Hanzawa Chapter 25: Radicals in stereoselective C-C bond formation Josep Bonjoch, Ben Bradshaw and Faiza Diaba Chapter 26: Trifluoromethyl (CF3) group insertion methods instereoselective synthesis Tsutomu Konno Chapter 27: Stereoselective organocatalyzed C Cbond-forming reactions Kazuo Nagasawa and Koji Yasui Chapter 28: Enzyme-catalysed stereoselective C C bondformation reactions in total syntheses Adeline Ranoux and Ulf Hanefeld 2.2.
Compiling material from leading contributors into one cohesive resource, this practical resource on synthetic methodology, reaction mechanisms, and applications for medicinal chemistry and drug discovery explores strategy and interdisciplinary work, laboratory synthesis for natural products, the preparative aspects of stereoselective synthesis for drugs, natural products, and potential biologically active compounds.
Chapter 54: Chiral chromatographic methods in the analysis andpurification of enantiomers Arnau Novell and Cristina Minguillon Chapter 55: X-Ray crystallography and 1H NMR anisotropy methodsfor determination of absolute configurations Nobuyuki Harada Chapter 56: Crystallization based separation ofenantiomers Yaling Wang and Alex Chen Chapter 57: Enzymatic dynamic kinetic resolution instereoselective synthesis Francisca Rebolledo, Javier Gonzalez-Sabin, andVicente Gotor Subject index.
Clark Chapter 46: Stereoselective carbon sulfur (C S) bondformation Kyungsoo Oh Chapter 47: Stereoselective methods for carbon-phosphorus(C P) bond formation Marcin Kalek and Jacek Stawinski Chapter 48: Transition-metal-catalyzed asymmetric sulfoxidationin drug and natural product synthesis Alessandro Scarso and Giorgio Strukul PART 3: METHODS OF ANALYSIS AND CHIRAL SEPARATION Chapter 49: NMR-Spectroscopy in drug and natural productanalysis Stanisuaw Witkowski and Iwona Wawer Chapter 50: Determination of enantiomeric purity and absoluteconfiguration by NMR spectroscopy Thomas J.
STEREOSELECTIVE FORMATION OF OTHER C HETEROATOM ANDOTHER BONDS Chapter 42: Stereoselective halogenations Chong Kiat Tan, Yi Zhao, Jing Zhou and Ying-Yeung Yeung Chapter 43: Stereoselective synthesis of halogenated naturalproducts Takehiko Yoshimitsu Chapter 44: Asymmetric fluorination methods: application in thestereoselective synthesis of fluorinated drugs Vincent Bizet and Dominique Cahard Chapter 45: Enzymatic halogenation in stereoselectivesynthesis Cormac D.
STEREOSELECTIVE METHODS FOR C O BOND FORMATION Chapter 34: Transition-metal-catalyzed stereoselectiveoxidations in drug and natural product synthesis Alessandro Scarso and Giorgio Strukul Chapter 35: Asymmetric epoxidation in stereoselectivesynthesis Zhicai Yang Chapter 36: Biocatalytic asymmetric oxidations instereoselective synthesis Anett Schallmey, Pablo Dominguez de Maria and PaulaBracco Chapter 37: Ether transfer methodology: application to thesynthesis of polyketide natural products Eric Stefan and Richard E.
STEREOSELECTIVE METHODS FOR C H BOND FORMATION Chapter 29: Stereoselective hydrogenation of C=C bonds:application to drug and natural product synthesis Natalia Andrushko and Vasyl Andrushko Chapter 30: Asymmetric hydrogenation of C=O and C=N bonds instereoselective synthesis Natalia Andrushko and Vasyl Andrushko Chapter 31: Asymmetric protonation of carbanions and polardouble bonds: application to total syntheses Thomas Poisson and Shu Kobayashi Chapter 32: Organocatalytic reduction in stereoselectivesynthesis Felix Kortmann and Adriaan Minnaard Chapter 33: Biocatalytic asymmetric reduction of C=O andactivated C=C bonds in stereoselective synthesis Tomoko Matsuda, Rio Yamanaka and Kaoru Nakamura 2.3.
Clarke Chapter 15: Intramolecular oxycarbonylation in stereoselectivesynthesis Tibor Gracza Chapter 16: Stereoselective cycloaddition reactions Tae-Kyung Lee and Jung-Mo Ahn Chapter 17: Sigmatropic rearrangements in stereoselectivesynthesis Brinton Seashore-Ludlow and Peter Somfai Chapter 18: Ring contraction reactions in the total synthesis ofbiologically active natural products Luiz F.
Coltart Chapter 8: Asymmetric aldol reactions in the total syntheses ofnatural products Seijiro Hosokawa Chapter 9: Asymmetric Michael addition and relatedreactions Pengfei Li, Jun Wang and Fuk Yee Kwong Chapter 10: Construction of polypropionate fragments in naturalproduct synthesis Maris Turks, Sylvain Laclef and Pierre Vogel Chapter 11: Organocatalytic conjugate addition instereoselective synthesis Adrien Quintard and Alexandre Alexakis Chapter 12: Stereoselective Nozaki-Hiyama-Kishi reaction Pat Guiry and Grainne Hargaden Chapter 13: Transition-metal-catalyzed asymmetric C Ccross-couplings in stereoselective synthesis VasilikiSarli Chapter 14: Asymmetric hydroformylation, hydroxy- andalkoxycarbonylation for stereoselective synthesis Jamie T.
Scott Chapter 4: Asymmetric phase-transfer catalysis Kohsuke Ohmatsu, Daisuke Uraguchi, and Takashi Ooi Chapter 5: Microwave-assisted stereoselective synthesis Yoann Coquerel, Evelina Colacino, Jean Rodriguez, Jean Martinezand Frederic Lamaty Chapter 6: Application of micro reactor methodology for organicsynthesis Paul Watts and Charlotte Wiles PART 2: STEREOSELECTIVE SYNTHESIS BY BOND FORMATION 2.1.
ft., former Hercules/PFW facility in Middletown, NY; Fleurchem produces a full range of natural isolates, synthetic chemicals & specialities, essential oils and flavors.