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Synthesis, Characterization and Chelating Properties of Novel ..

Habibullah Khalilullah et al 94 prepared some novel pyrazoline derivatives containing 1,4-dioxane ring system . Some of the synthesized compounds were evaluated for antihepatotoxic activity against CCl4-induced hepatotoxicity in rats. Compounds showed significant activity comparable to standard drug silymarin.

Pyrazoline derivatives (9a) were synthesized by F. Hayat et al 87and evaluated for in vitro antiamoebic activity against HM1: IMSS strain of E. Histolytica. Compound showed promising antiamoebic activity. M.Y. Wani et al 88 reported novel tetrazole embedded 1,3,5-trisubstituted pyrazoline derivatives (9b) as Entamoeba histolytica growth inhibitors.


“Synthesis and Activity of 2-Pyrazoline Derivatives ..

Erol," Synthesis and antidepressant activities of some 3,5-diphenyl-2-pyrazolines.

Dohut, C., Kaishap, P. P. and Chetia, D.(2013) Synthesis and study of analgesic, anti-inflammatory activities of 3-methyl-5-pyrazolone derivatives. Int J Pharm Pharm Sci., 5(1), pp. 86-90.

Hawaiz, F.E , Hussein, A. J. and Kreem, M S. (2014) One-pot three-component synthesis of some new azo-pyrazoline derivatives. European J Chem., 5(2), pp. 233‐236.

PDF Downloads : Oriental Journal of Chemistry

Siham A, Lahsasni F, Hamad Al K, Nabilah A A: Synthesis, characterization and evaluation of antioxidant activities of some novel chalcones analogues. Chemistry Central Journal 2014, 8:32

Synthesis and antimicrobial properties of novel 2,5-disubstituted 1,3,4-oxadiazoles.

Purpose:The aim of this article is to synthesize, characterize and evaluate the antimicrobial activity of certain novel 3-methyl-5-oxo-4-(phenyl hydrazono)-4,5-dihydro-pyrazol-1-yl]-acetic acid N|-(4-substituted thiazol-2-yl)-hydrazides.Methods:The synthesized compounds were characterized by elemental analysis and IR, NMR and mass spectral data. The antimicrobial activity of novel compounds was evaluated by broth dilution method.Results:XVe, XVf and XVg have shown better antibacterial activity than other compounds of the series. XVa, XVc, XVd and XVe have shown better antifungal activity than the other compounds of the series.Conclusion:All compounds were found to exhibit fair degree of antimicrobial activity.

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Regional Centre of Advanced Technologies and Materials


Gong, Z-L., Zheng, L-W., Zhao, B-X., Yang, D-Z., Lv, H-S., Liu, W-Y. and Lian S. The Synthesis, X-ray crystal structure and optical properties of novel 1, 3, 5- triaryl pyrazoline derivatives. Photochemistry and Photobiology, 2010, 209, 49-55.

Research Articles - Current Issues | INTERNATIONAL …

Zeng, Y.M., Chen, S.Q. and Liu, F.M. Synthesis and crystal structure of new thiazolyl-pyrazoline derivatives bearing 1, 2, 4-triazole moiety. The Journal of Chemical Crystallography, 2012, 42, 24-28.

Physics - Home - University of Lucknow

Varghese, B., Al-Busafi, S.N., Suliman, F.O and Al-Kindy, S.M.Z. Synthesis, spectroscopic characterization and photophysics of a novel environmentally sensitive dye 3-naphthyl-1-phenyl-5(4-carboxyphenyl)-2-pyrazoline. Journal of Luminescence, 2015, 159, 9-16.

Molecules | April 2014 - Browse Articles

Wang, S.Q., Gao, Y., Wang, H.Y., Zheng, X.X., Shen, S.L., Zhang, Y.R. and Zhao B.X. Synthesis, X-ray crystal structure and optical properties of novel 1,3,5-triarylpyrazoline derivatives and the fluorescent sensor for Cu2+. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy., 2013, 106, 110-117.

Molecules, an international, peer-reviewed Open Access journal.

Singh, P., Negi, J.S., Singh, K., Pant, G.J., Rawat, M.S.M. and Joshi, G.C. Synthesis and structure dependent photophysical properties of novel 2-pyrazolines. Synthetic Metals, 2012, 162, 1977-1980.

Staff Profile - City University of Hong Kong

Kumar, C.K., Trivedi, R., Kumar, K.R., Giribabu, L. and Sridhar, B. Synthesis, Characterization, electrochemistry and optical properties of new 1,3,5-trisubstituted ferrocenyl pyrazolines and pyrazoles containing sulfonamide moiety. Journal of Organometallic Chemistry, 2012, 718, 64-73.

Molecules | October 2017 - Browse Articles

Wang, H.Y., Shi, J.J., Chen, G., Xu, X.P. and Ji, S.J. Synthesis and characteristics of novel benzothiazoyl-pyrazoline derivatives containing carbazole. Synthetic Metals, 2012, 162, 241-246.

2017 / Volume 16 - EXCLI Journal

Among nitrogen containing five membered heterocycles, pyrazolines and related heterocycles demonstrate various types of biological activities. The pharmaceutical importance of these compounds lies in the fact that they can be effectively utilized as antibacterial, antifungal, antidepressant, anti inflammatory, antioxidant, antiviral, antiparasitic, antitubercular and antitumor, insecticidal agents.- On the other hand the pharmacological properties of thiazoles have been well established. They also exhibit broad spectrum of chemotherapeutic properties such as antibacterial, antifungal and antitubercular, anti-HIV, anticonvulsant, anticancer, anti-inflammatory and analgesic.- Keeping in view the easily reproducible and feasible synthetic routes for synthesis and the importance of these two moieties namely, pyrazolines and thiazoles in the field of medicine, the authors have made an attempt to synthesize some novel compounds containing both these moieties and investigated for the possible antimicrobial activity.

2017 / Volume 16 Original articles

Havrylyuk, D., Zimenkovsky, B., Karpenko, O., Grellier, P. and Lesyk, R. Synthesis of pyrazoline- thiazolidinone hybrids with trypanocidal activity. European Journal of Medicinal Chemistry, 2014, 85, 245-254.

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