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Promotes synthesis of prothrombin - think-forex …

Vitamin K intake of more than 250 µg/day was shown to decrease warfarin sensitivity in anticoagulated patients consuming regular diets. Patients that were allocated to an 80% decrease of vitamin K intake increased International Normalized Ratio (INR) by almost 30% 7 days after the intervention. Similarly, it was estimated by dietary records that for each increase in 100 µg of vitamin K intake, the would be reduced by 0.2.

Regarding the coagulation, vitamin K is important for the hepatic synthesis of coagulation factors II (prothrombin), X (clotting factors), and protein C with his cofactor protein S (endogenous anticoagulants).

Substance that promotes synthesis of prothrombin: ..

required for the synthesis of clotting factors (prothrombin) B

What promotes synthesis of prothrombin

It is absorbed from the upper small intestine with the help of bile or bile salts and pancreatic juices and then carried to the liver for the synthesis of prothrombin, a key blood-clotting factor.

Patients receiving warfarin who have unstable control of anticoagulation have a significantly lower intake of dietary vitamin K compared with their stable counterparts. Vitamin K supplementation (150 µg oral vitamin K vs placebo) resulted in a significantly greater decrease in standard deviation of international normalized ratio (INR) compared with placebo and a significantly greater increase in percentage time within target range. Concomitant supplementation of vitamin K, perhaps through reducing the relative day-to-day variability in dietary vitamin K intake, can significantly improve anticoagulation control in patients with unexplained instability of response to warfarin.

Prothrombin synthesis in the dog | AJP Legacy

A long-term oral anticoagulant therapy results in suppression of the synthesis of both vitamin K-dependent coagulation factors and Protein C, but the production of the coagulant and anticoagulant proteins is well-balanced.

CELLULAR STUDY OF DRUG ALTERATION OF PROTHROMBIN SYNTHESIS MARION I ..

.Helps to maintain nerve cells/-Reforms folate coenzyme/ -Helps to break down some fatty acids and amino acids/

-Synthesis of methionine/ Deficiency--Pernicious anemia




a) Aspartic acid

b) Ascorbic acid

c) Adipic acid

d) Saccharic acid


a) Vitamin B1

b) Vitamin B2

c) Vitamin B6

d) Vitamin B12


a) Change of prothrombin into thrombin

b) Synthesis of prothrombin

c) Change of fibrinogen to fibrin

d) Formation of thromboplastin


a) Vitamin C

b) Vitamin D

c) Vitamin A

d) Vitamin E


a) Scurvy

b) Antibody synthesis

c) Rickets

d) Pellagra


a) Vitamin K

b) Vitamin B12

c) Vitamin A

d) Vitamin B6


a) Vitamin C

b) Vitamin K

c) Vitamin A

d) Vitamin B complex


a) Vitamin E - Tocopherol

b) Vitamin D - Riboflavin

c) Vitamin B - Calciferol

d) Vitamin A – Thiamine




a) Vitamin A

b) Vitamin B

c) Vitamin K

d) Vitamin E


a) Vitamin C- Scurvy

b) Vitamin B2- Pellagra

c) Vitamin B2- Pernicious Anaemia

d) Vitamin B6- Beri beri


a) Retinol- Xerophthalmia

b) Cobalamine-Beri beri

c) Calciferol- Pellagra

d) Ascorbic acid- Scurvy


a) Vitamin A- Xerophthalmia

b) Vitamin D- Rickets

c) Vitamin K- Beriberi

d) Vitamin C-Scurvy





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it appears that vitamin Ki promotes prothrombin synthesis by ..


What is the function of prothrombin

Vitamin K is required for

a) Change ofprothrombin into thrombin

b) Synthesisof prothrombin

c) Change offibrinogen to fibrin

d) Formationof thromboplastin



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